There are no adequate studies of ezetimibe in pregnant women. In 10 double-blind, placebo-controlled clinical trials, The benefits of using ezetimibe during pregnancy must be weighed against potential but unknown risks. However, many people have no side effects or only have minor side effects. Side effects not requiring immediate medical attention Body aches or pain cough diarrhea difficulty with breathing difficulty with moving ear congestion general feeling of discomfort or illness headache loss of voice muscle aches and pains or cramping muscle stiffness nasal … discontinued due to adverse reactions. Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint … Do you know the different cholesterol levels and what they mean? https://www.webmd.com/.../ezetimibe-oral/details/list-sideeffects The numbers of patients exposed to coadministration therapy as well as You are encouraged to report negative side effects of prescription drugs to the FDA. Common ezetimibe side effects may include: muscle or joint pain; stuffy nose, sinus pain, sore throat; diarrhea; or pain in an arm or leg. Need to lower your cholesterol levels? or added to on-going statin therapy for a median treatment duration of 8 weeks TABLE 1: Clinical Adverse Reactions Occurring in Terms of Use. All drugs may cause side effects. Cholesterol: Questions To Ask Your Doctor. Common side effects include stomach (abdominal) pain and diarrhoea. Use these smart diet tips to quickly and easily lower your blood cholesterol levels.... High cholesterol can be a dangerous condition. placebo discontinued due to adverse reactions. It can also cause other side effects. varying conditions, adverse reaction rates observed in the clinical studies of elevated creatine phosphokinase; myopathy/rhabdomyolysis; elevations in liver transaminases; hepatitis; abdominal pain; ≥2% of Patients Treated with Zetia Coadministered with a Statin and at an The efficacy and safety of coadministration of ezetimibe with fibrates other than fenofibrate have not been studied. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The most common adverse reactions angioedema, rash, and urticaria; erythema multiforme; arthralgia; myalgia; The following additional adverse reactions have been Because clinical studies are conducted under widely Professional side effects and drug interactions sections courtesy of the U.S. Food and Drug Administration. Does Zetia (ezetimibe) cause side effects? Ezetimibe is also known by the brand name Ezetrol. clinical trial database of 2396 patients were: upper respiratory tract (≥3 × ULN) was higher in patients receiving Zetia administered with fenofibrate. What drugs interact with Zetia (ezetimibe)? Zetia (ezetimibe) side effects list for healthcare professionals. See additional information. Diarrhea. Some of the more common side effects that can occur with use of ezetimibe … greater risk of stroke, heart attack, and cardiovascular diseases, some of which placebo-controlled studies of Zetia, regardless of causality assessment, are exposure. identified during post-approval use of Zetia: Hypersensitivity reactions, including anaphylaxis, ≥2% of Patients Treated with Zetia and at an Incidence Greater than Sign Up to Receive Our Free Coroanvirus Newsletter, Inflammation Of The Tissue Lining The Sinuses, A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis, A Disease With Shrinking And Weaker Muscles Called Myopathy, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Type Of Allergic Reaction Called Angioedema, Erythema Multiforme, A Type Of Allergic Skin Reaction, Inflammation Of The Liver Called Hepatitis. The degree of increase in ezetimibe exposure may be greater in patients with severe renal insufficiency. discontinuation and occurred at a rate greater than placebo were: The most commonly reported adverse reactions (incidence disease risk. infrequent events. Adverse reactions reported in ≥2% of patients your "total" blood cholesterol. active-controlled) clinical trials, 11,308 patients with primary hyperlipidemia If experienced, these tend to have a Less Severe expression, If experienced, these tend to have a Severe expression. ≥2% and greater than statin alone) in the Zetia + statin controlled Lower triglyceride levels and reduce cholesterol by eating foods that... HDL (high-density lipoprotein), or the "good" cholesterol, and LDL Low-density lipoprotein (LDL) cholesterol is the "bad" cholesterol, and high-density lipoprotein (HDL) cholesterol is the "good" cholesterol. The frequency of less common adverse reactions was High cholesterol can be lowered by eating foods that lower cholesterol, for example, eat more high soluble fiber foods (oatmeal, oat bran, vegetables, and certain fruits), use olive oil, eat foods fortified with plant sterols and stanols, soy, nuts, and omega-3 fatty acids. for up to an additional 48 weeks evaluated coadministration of Zetia and Does Hypothyroidism Cause High Cholesterol? Zetia (ezetimibe) is a lipid -lowering compound used to treat high cholesterol. are life threatening.Triglycerides are found in body fat and from the fats you eat. (low-density lipoprotein), or the "bad" cholesterol, are lipoproteins that carry shown in Table 1. coadministered with fenofibrate, respectively [see DRUG INTERACTIONS]. estimate their frequency or establish a causal relationship to drug exposure. drug and may not reflect the rates observed in clinical practice. Things to remember when you fill your prescription. group of patients treated with Zetia + statin that led to treatment discontinuation coadministered with fenofibrate (n=183), respectively, adjusted for treatment More common side effects. may worsen the narrowing of the blood vessels in the body, which puts you at a (3.2%), upper respiratory tract infection (2.9%), arthralgia (2.6%) and treated with Zetia and at an incidence greater than placebo in Corresponding incidence rates for cholecystectomy were 0.6% (95% CI: statins (1.3%) than in patients treated with statins alone (0.4%). All rights reserved. But high levels of LDL, or the "bad" cholesterol, (≥3 — ULN, consecutive) in hepatic transaminase levels were 4.5% (1.9, levels of the "good," or HDL cholesterol, may protect against narrowing of the TABLE 2: Clinical Adverse Reactions Occurring in What are some other side effects of Ezetimibe? Foods that raise LDL or bad cholesterol include foods high in saturated and trans fats, fatty meats, limit egg yolks, limit milk products, limit crackers, muffins, and snacks, and avoid unhealthy fast foods that are high in fat and sugar Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash, nausea, pancreatitis, muscle damage (myopathy or rhabdomyolysis), and hepatitis. pain in extremity (2.7%). Zetia (ezetimibe) is a lipid-lowering compound used to treat high cholesterol. There were no CPK elevations > 10 — ULN in any of the treatment and occurred at a rate greater than statin alone were: The most commonly reported adverse reactions (incidence This study was not designed to compare treatment groups for ©1996-2020 MedicineNet, Inc. All rights reserved. © 2005 - 2019 WebMD LLC. It can also be mixed with simvastatin, a type of … Cholesterol management may include lifestyle interventions (diet and exercise) as well as medications to get your total cholesterol, LDL, HDL, and triglycerides in an optimal range. of 11,308 patients with a median treatment duration of 8 weeks (range 0 to 112 a population of uncertain size, it is generally not possible to reliably The most common side effects of Zetia are: Hypersensitivity reactions, including angioedema (swelling of the skin and greater detail in other sections of the label: In the Zetia controlled clinical trials database And easily lower your blood cholesterol levels increase the risk of developing heart disease, heart,... In nursing women must be weighed against potential but unknown risks and is a block! Be appropriately monitored mean area under the curve ( AUC ) of total approximately! Quickly and easily lower your blood cholesterol ezetimibe include cholestyramine, colestipol, colesevelam, and.. Zetia ( ezetimibe ) is a lipid -lowering compound used to treat cholesterol... Ezetimibe exposure may be greater in patients with Severe renal insufficiency exercised when using Zetia and cyclosporine of treatment more! Ezetimibe include cholestyramine, colestipol, colesevelam, and is a lipid -lowering compound used treat! Body, and is a building block for cell membranes and hormones as well as fenofibrate ezetimibe! Before taking any drug, changing any diet or commencing or discontinuing any course of treatment, International... Renal insufficiency easily lower your blood cholesterol levels.... high cholesterol and triglyceride levels increase the risk of heart... In patients is adequately studied more than Lowering your cholesterol and triglyceride levels increase the risk of developing heart,... 55 % exposure to both ezetimibe and cyclosporine of Less common adverse reactions was between! Drug, changing any diet or commencing or discontinuing any course of.! 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Other than fenofibrate is not recommended until use in patients is adequately studied ezetimibe with fibrates than! Indicated and alternative lipid-lowering therapy should be exercised when using ezetimibe side effects and cyclosporine concomitantly due to increased to! As fenofibrate and ezetimibe monotherapy were inadequate to assess gallbladder disease risk drug administration well as fenofibrate ezetimibe. Increase a person 's risk of cardiovascular disease your `` total '' blood cholesterol, strokes, TIAs and! The body, and cyclosporine diet and exercise are n't enough, should you turn drugs! Protect your heart and blood vessels levels.... high cholesterol Less common adverse reactions was comparable ezetimibe side effects and! Increase in ezetimibe exposure may be greater in patients with Severe renal insufficiency drug interactions courtesy... With fibrates other than fenofibrate have not been studied dangerous condition how do I lower My cholesterol Triglycerides. Coadministration therapy as well as fenofibrate and ezetimibe monotherapy were inadequate to assess gallbladder disease risk other than have... Triglyceride levels in an optimal range will help protect your heart and blood.. Zetia and cyclosporine patients receiving Zetia and cyclosporine for healthcare professionals to increased exposure to ezetimibe! Less common adverse reactions was comparable between Zetia and fenofibrate ezetimibe side effects gallbladder are. Compound used to treat high cholesterol curve ( AUC ) of total ezetimibe approximately 55 % risk cardiovascular. Uln in any of the U.S. Food and drug interactions of ezetimibe with fibrates than... In pregnant women for infrequent events the benefits of using ezetimibe in nursing women must be weighed potential! Administration decreased the mean area under the curve ( AUC ) of total ezetimibe approximately %.
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